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Symbol
Name
ID
Plau
plasminogen activator, urokinase
MGI:97611
Phenotype annotations related to cardiovascular system
*Aspects of the system are reported to show a normal phenotype.
Darker colors indicate more annotations
Human Phenotypes
Joint hemorrhage
Bruising susceptibility
Mitral valve prolapse
Mitral regurgitation
Disease(s) Associated with PLAU
mitral valve prolapse
Quebec platelet disorder

Mouse Phenotypes
cardiovascular system phenotype
decreased susceptibility to induced choroidal neovascularization
heart left ventricle hypertrophy
enlarged heart
cardiac fibrosis
cardiac interstitial fibrosis
increased ventricle muscle contractility
heart inflammation
Availability Mouse Genotype
Plautm1Mlg/Plautm1Mlg
Tg(MSR1-Plau)1Ddi/0
Tg(Mup3-Plau)350-2Eps/0 *

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory